Phytochemicals as Dynamic Surface Ligands To Control Nanoparticle–Protein Interactions

Synthetic multivalent ligands in the exploration of cell-surface interactions.

Processes such as cell-cell recognition and the initiation of signal transduction often depend on the formation of multiple receptor-ligand complexes at the cell surface. Synthetic multivalent ligands are unique probes of these complex cell-surface-binding events. Multivalent ligands can be used as inhibitors of receptor-ligand interactions or as activators of signal transduction pathways. Emer...

microleakage evaluation in regard to cavo-surface designs & treatments

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Phytochemicals Components as Bioactive Foods

Phytochemicals as radioprotective agentsA Review

The development of radioprotective agents has been a subject of intense research in view of their potential for use within a radiation environment, such as space exploration, radiotherapy and even nuclear war. Since no ideal, safe synthetic radioprotectors are available to date, the search for alternative sources, including plants, has been on-going for several decades. In the Traditional India...

Dynamic control of chirality in phosphine ligands for enantioselective catalysis

Chirality plays a fundamental role in biology and chemistry and the precise control of chirality in a catalytic conversion is a key to modern synthesis most prominently seen in the production of pharmaceuticals. In enantioselective metal-based catalysis, access to each product enantiomer is commonly achieved through ligand design with chiral bisphosphines being widely applied as privileged liga...